Factors associated with liver injury and prognosis in advanced cancer patients treated with immune checkpoint inhibitors.

Shun KanekoYasuhiro AsahinaMina NakagawaMiyako MurakawaYasunari MiyazakiTakahiro AsakageShohei FukudaTakeshi NamikiYoshihito KanoMasashi NagataJun TsuchiyaMasato MiyoshiFukiko Kitahata-KawaiSayuri NittaYasuhiro ItsuiSei KakinumaRyuichi Okamoto

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2023)

The incidence of irLI was significantly higher in patients treated with anti-cytotoxic T-lymphocyte-associated protein-4 agents. Even in patients with pre-existing grade 1 aspartate aminotransferase/alanine aminotransferase elevation, appropriate follow-up and control of the irLI can improve the prognosis.

Keyphrases

liver injury
advanced cancer
drug induced
palliative care
risk factors
peripheral blood