The impact of diuretic use and ABCG2 genotype on the predictive performance of a published allopurinol dosing tool.

Daniel F B WrightNicola DalbethAmanda J Phipps-GreenTony R MerrimanMurray L BarclayJill DrakePaul TanAnne HorneLisa K Stamp

Published in: British journal of clinical pharmacology (2018)

The dosing tool produced acceptable maintenance dose predictions for patients not taking diuretics. Inclusion of ABCG2 genotype and a revised adjustment for diuretics would further improve the performance of the dosing tool.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
systematic review
randomized controlled trial
cancer stem cells
meta analyses