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Glycaemic control and macrovascular and microvascular outcomes in type 2 diabetes: Systematic review and meta-analysis of cardiovascular outcome trials of novel glucose-lowering agents.

Setor Kwadzo KunutsorFrancesco ZaccardiVictoria G BalasubramanianClare L GilliesVanita R ArodaSamuel SeiduMelanie Jane DaviesKamlesh Khunti F MedSci
Published in: Diabetes, obesity & metabolism (2024)
SGLT-2is and GLP-1RAs showed consistent risk reductions in macrovascular and microvascular outcomes. The vascular benefits of SGLT-2is and GLP-1RAs in patients with T2D extend beyond mere glycaemic control.
Keyphrases
  • type diabetes
  • systematic review
  • glycemic control
  • meta analyses
  • cardiovascular disease
  • wild type
  • blood glucose
  • insulin resistance
  • randomized controlled trial
  • adipose tissue
  • skeletal muscle