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FOXM1 overexpression is associated with adverse outcome and predicts response to intravesical instillation therapy in stage pT1 non-muscle-invasive bladder cancer.

Johannes BreyerRalph M WirtzPhilipp ErbenSebastien RinaldettiThomas S WorstRobert StoehrMarkus EcksteinDanijel SikicStefan DenzingerMaximilian BurgerArndt HartmannWolfgang Otto
Published in: BJU international (2018)
High FOXM1 expression was associated with adverse clinical and pathological features and worse outcomes, and predicted response to intravesical instillation therapy in patients with stage pT1 NMIBC.
Keyphrases
  • muscle invasive bladder cancer
  • poor prognosis
  • emergency department
  • stem cells
  • type diabetes
  • adipose tissue
  • transcription factor
  • metabolic syndrome
  • bone marrow
  • skeletal muscle
  • mesenchymal stem cells
  • weight loss