Anti-diabetic and gut microbiota modulation effects of sacha inchi (Plukenetia volubilis L.) leaf extract in streptozotocin-induced type 1 diabetic mice.

Jinming LinJiamin WenNan XiaoYu-Tong CaiJie XiaoWenhao DaiJian-Ping ChenKe-Wu ZengFengsong LiuBing DuPan Li

Published in: Journal of the science of food and agriculture (2022)

Treatment with PWE can ameliorate hyperglycemic symptoms in STZ-induced T1DM mice, and the anti-diabetic effect of PWE was related to the amelioration of gut microbial structural disorder and the enrichment of functional bacteria. © 2022 Society of Chemical Industry.

Keyphrases

diabetic rats
oxidative stress
high glucose
type diabetes
drug induced
wound healing
microbial community
high fat diet
metabolic syndrome
endothelial cells
physical activity
adipose tissue
high fat diet induced
smoking cessation