Signal regulatory protein alpha blockade potentiates tumoricidal effects of macrophages on gastroenterological neoplastic cells in syngeneic immunocompetent mice.
Tomoyuki AbeYuka TanakaJinlian PiaoNaoki TanimineNaohide OueTakao HinoiNoel Verjan GarciaMasayuki MiyasakaTakashi MatozakiWataru YasuiHideki OhdanPublished in: Annals of gastroenterological surgery (2018)
SIRPα mAb augmentation of macrophage phagocytic activity may represent an effective treatment strategy for human gastrointestinal tumors.