Evidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure.

Jenny WilshawA BoswoodY M ChangC J SandsS CamuzeauxM R LewisD XiaD J Connolly

Published in: Metabolomics : Official journal of the Metabolomic Society (2022)

The canine metabolome appears to change as MMVD progresses. Findings from this study suggest that in HF myocardial metabolism may be characterised by reduced β-oxidation. This proposed explanation warrants further research.

Keyphrases

heart failure
fatty acid
left ventricular
atrial fibrillation
acute heart failure
pulmonary hypertension
hydrogen peroxide
nitric oxide
cardiac resynchronization therapy