SEPHS1 promotes SMAD2/3/4 expression and hepatocellular carcinoma cells invasion.

Shu YangHongying ZhangHua YangJin ZhangJiao WangTing LuoYangfu JiangHui Hua

Published in: Experimental hematology & oncology (2021)

SEPHS1 is a positive regulator of TGF-β/SMAD signaling that is up-regulated in HCC. Increased SEPHS1 expression may indicate poor prognosis for patients with HCC.

Keyphrases

poor prognosis
long non coding rna
transforming growth factor
epithelial mesenchymal transition
transcription factor
cell migration