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Genomic prediction of the polled and horned phenotypes in Merino sheep.

Naomi DuijvesteijnSunduimijid BolormaaHans D DaetwylerJulius H J van der Werf
Published in: Genetics, selection, evolution : GSE (2018)
Our results show that prediction accuracy is high using a single SNP, but does not reach 1 since the causative mutation is not genotyped. Incomplete penetrance or allelic heterogeneity, which can influence expression of the phenotype, may explain why prediction accuracy did not approach 1 with any of the genetic models tested here. Nevertheless, a breeding program to eradicate horns from Merino sheep can be effective by selecting genotypes GG of SNP OAR10_29458450 or TT of SNP OAR10_29546872.1 since all sheep with these genotypes will be non-horned.
Keyphrases
  • genome wide
  • high density
  • copy number
  • dna methylation
  • poor prognosis
  • genetic diversity
  • single cell
  • quality improvement