Slope of Kidney Function and Its Association with Longitudinal Mortality and Cardiovascular Disease among Individuals with CKD.

Paula F OrlandiDawei XieWei YangJordana B CohenRajat DeoAna C RicardoSarah SchraubenXue WangL Lee HammJiang HeJames H SondheimerKrishna KallemRaymond TownsendDominic RajAfshin ParsaAmanda H AndersonHarold I Feldmannull nullnull null

Published in: Journal of the American Society of Nephrology : JASN (2020)

In a cohort of individuals with moderate to severe CKD, we observed steep declines of eGFR were associated with progressively increasing risks of death and cardiovascular events; however, we found no increased risks associated with eGFR improvement. These findings support the potential value of eGFR slopes in clinical assessment of adults with CKD.

Keyphrases

cardiovascular events
cardiovascular disease
small cell lung cancer
epidermal growth factor receptor
chronic kidney disease
tyrosine kinase
coronary artery disease
human health
risk assessment
type diabetes
high intensity
cross sectional
risk factors
metabolic syndrome