Independent expression of circulating and tissue levels of PD-L1: correlation of clusters with tumor metabolism and outcome in patients with non-small cell lung cancer.

Fabio GrizziAngelo CastelloDorina QehajajLuca ToschiSabrina RossiDaniela PistilloValentina PaleariGiulia VeronesiPierluigi NovellisSimona MonterisiRossana MineriDaoud RahalEgesta Lopci

Published in: Cancer immunology, immunotherapy : CII (2019)

Plasma levels of PD-L1 are independent of the expression of PD-1/PD-L1 in NSCLC tumor tissue and, when combined with other clinical-pathological parameters, allow for the identification of clusters with different outcomes.

Keyphrases

poor prognosis
small cell lung cancer
binding protein
long non coding rna
type diabetes
brain metastases
tyrosine kinase
glycemic control