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Effect of sarcopenia and frailty on outcomes among patients with brain metastases.

Mervyn Jun Rui LimZheting ZhangYilong ZhengIvan Wei Loon KhooRhianne Caitlin Vaz Xin YingSophie Jia Qian KohEthanyn LimPei Ing NgamBetsy SoonYing Liang LowLi Feng TanKejia TeoVincent Diong Weng NgaTseng Tsai Yeo
Published in: Journal of neuro-oncology (2024)
In patients with surgically treated brain metastases, psoas cross-sectional area was an independent risk factor for mortality and recurrence, while post-operative CFS was an independent risk factor for mortality. Post-operative frailty and increase in CFS significantly increased duration of hospitalization. Measurement of psoas cross-sectional area and CFS may aid in risk stratification of surgical candidates for brain metastases.
Keyphrases
  • brain metastases
  • cross sectional
  • small cell lung cancer
  • community dwelling
  • cardiovascular events
  • risk factors
  • skeletal muscle
  • cardiovascular disease
  • type diabetes
  • metabolic syndrome
  • weight loss
  • newly diagnosed