Simplified and accessible [ 18 F]F-AraG synthesis procedure for preclinical PET.

Antonia A Högnäsbacka Miguel A Cortés González Christer Halldin Magnus Schou

Published in: Journal of labelled compounds & radiopharmaceuticals (2022)

The PET tracer [ 18 F]F-AraG, an arabinosyl guanine analog, has shown promise for visualizing activated T cells in multiple diseases. Herein, a practitioner's protocol is described, in which the PET tracer is prepared using minimal equipment and manual actions, making it widely accessible for preclinical applications.

Keyphrases

positron emission tomography
pet imaging
computed tomography
pet ct
randomized controlled trial
cell therapy
stem cells
big data
artificial intelligence
machine learning
bone marrow
living cells
fluorescent probe