Design and protocol for a cluster randomised trial of enhanced diagnostics for tuberculosis screening among people living with HIV in hospital in Malawi (CASTLE study).

Rachael M BurkeSaulos NyirendaHussein H TwabiMarriott NliwasaElizabeth JoekesNaomi WalkerRose NyirendaAnkur Gupta-WrightKatherine FieldingPeter MacPhersonElizabeth L Corbett

Published in: PloS one (2022)

Both DCXR-CAD and FujiLAM have potential clinical utility and may have complementary diagnostic performance. To our knowledge, this is the first randomised trial to evaluate these tests among hospitalised PLHIV.

Keyphrases

healthcare
study protocol
open label
randomized controlled trial
coronary artery disease
mycobacterium tuberculosis
adverse drug
pulmonary tuberculosis
emergency department
acute care
hepatitis c virus