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A multimodal pain protocol for treatment of vaso-occlusive crisis in patients with sickle cell disease: Implementation and evaluation.

Manouk AdmiraalJonathan van DaalenMichael W J RittJoost DekkerCharlotte F J van TuijnErfan NurMarkus W HollmannHenning HermannsJeroen HermanidesBart J Biemond
Published in: European journal of haematology (2023)
The implementation of a pain protocol using multimodal analgesia for VOC in patients with SCD appeared to be feasible and facilitated rapid administration of opioids. Controlled trials are needed to investigate the effectiveness of multimodal analgesia on pain and should focus on patient reported outcome measures.
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