"Prompt" for PREEMPT: Dotting the I's and Crossing the T's With Ultrasound.

Ahmad Jasem Abdulsalam Pelin Analay Murat KaraAhmed Amine El OumriLevent Özçakar

Published in: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine (2024)

The management of chronic migraine (CM) underwent a significant shift with the introduction of onabotulinumtoxin A (BoNT-A) injections following the landmark PREEMPT trial in 2010. Despite its efficacy, the existing injection protocol lacks precision, prompting a call for revision in light of modern ultrasound (US)-guided techniques. This article highlights the potential of US-guided injections to enhance accuracy, safety, and efficacy in CM treatment. By providing real-time visualization and addressing anatomical variations, US guidance offers a promising avenue for optimizing BoNT-A delivery, minimizing adverse effects, and ensuring therapeutic success.

Keyphrases

ultrasound guided
magnetic resonance imaging
platelet rich plasma
total knee arthroplasty
randomized controlled trial
study protocol
clinical trial
combination therapy
risk assessment
climate change
replacement therapy