Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis.
Amandeep K DhillonMartin KummenMarius TrøseidSissel ÅkraEvaggelia LiaskouBjørn MoumMette VesterhusTom H KarlsenIngebjørg SeljeflotJohannes Roksund HovPublished in: Liver international : official journal of the International Association for the Study of the Liver (2018)
Primary sclerosing cholangitis patients show increased levels of circulating markers of bacterial translocation. High levels are associated with poor prognosis measured by transplantation-free survival, indicating that ongoing gut leakage could have clinical impact in primary sclerosing cholangitis.