Mass Spectrometry Imaging Techniques Enabling Visualization of Lipid Isomers in Biological Tissues.
Antonín BednaříkVadym PrysiazhnyiDominika BezdekováJens SoltwischKlaus DreisewerdJan PreislerPublished in: Analytical chemistry (2022)
This Feature focuses on a review of recent developments in mass spectrometry imaging (MSI) of lipid isomers in biological tissues. The tandem MS techniques utilizing online and offline chemical derivatization procedures, ion activation techniques such as ozone-induced dissociation (OzID), ultraviolet photodissociation (UVPD), or electron-induced dissociation (EID), and other techniques such as coupling of ion mobility with MSI are discussed. The importance of resolving lipid isomers in diseases is highlighted.
Keyphrases
- mass spectrometry
- high resolution
- liquid chromatography
- gas chromatography
- high performance liquid chromatography
- high glucose
- diabetic rats
- gene expression
- electron transfer
- ms ms
- fatty acid
- capillary electrophoresis
- machine learning
- high resolution mass spectrometry
- multiple sclerosis
- drug induced
- tandem mass spectrometry
- social media
- healthcare
- oxidative stress
- liquid chromatography tandem mass spectrometry
- health information
- hydrogen peroxide
- room temperature
- nitric oxide
- particulate matter
- deep learning
- air pollution