An interesting case of AL amyloidosis and MM: a complex scenario with cardiac involvement.
Manish GabaNaveen KumarAnkita PandeyArun DewanPublished in: BMJ case reports (2024)
Our patient presented with complaints of progressive shortness of breath for 1 month. She was diagnosed with a case of infiltrative type of restrictive cardiomyopathy (RCM) based on echocardiography and cardiac MRI findings. Her fat pad biopsy was suggestive of AL type of amyloidosis (AL). She was diagnosed with a case of multiple myeloma (MM) based on bone marrow biopsy findings with 48% plasma cells and a skeletal survey with lytic bone lesions on the skull, thus meeting the Crab criteria. We want to highlight the complex nature of this case and the difficulties associated with making a diagnosis. This case report presents an excellent opportunity to touch on the interesting topics of RCM, amyloidosis and MM.
Keyphrases
- multiple myeloma
- case report
- left ventricular
- bone marrow
- induced apoptosis
- ultrasound guided
- multiple sclerosis
- magnetic resonance imaging
- fine needle aspiration
- heart failure
- mesenchymal stem cells
- adipose tissue
- computed tomography
- cell cycle arrest
- bone mineral density
- cross sectional
- contrast enhanced
- signaling pathway
- oxidative stress
- diffusion weighted imaging