Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults.

Chia-Ling KuoZhiduo ChenPeiran LiuLuke C Pilling Janice C AtkinsRichard H FortinskyGeorge A KuchelBreno S Diniz

Published in: medRxiv : the preprint server for health sciences (2023)

Due to its associations and predictive value for all-cause mortality and multiple incident diseases, PAC has the potential to serve as a valuable tool for assessing the effects of geoscience-guided interventions. It facilitates the evaluation of risk for multiple conditions in a disease-free population; thereby, contributing to the prevention of initial diseases, which vary among individuals and may subsequently lead to additional comorbidities.

Keyphrases

physical activity
cardiovascular disease
type diabetes
metabolic syndrome
skeletal muscle
climate change
glycemic control