Luke C Pilling (L C Pilling)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 49

Top Topics

Cardiovascular Disease

Genome Wide Association Study

Myasthenia Gravis

Top Venues

medRxiv : the preprint server for health sciences

The pharmacogenomics journal

This page only lists publications with an associated author ORCID identifier.

Publications

Mitchell R Lucas, Janice C Atkins, Luke C Pilling, Jeremy D Shearman, David Melzer
HFE genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank. BMJ open 14 (3) (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, João Delgado, Chia-Ling Kuo, David Melzer, Luke C Pilling
Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone. The pharmacogenomics journal 24 (3) (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Chia-Ling Kuo, Peiran Liu, Zhiduo Chen, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
A proteomic signature of healthspan. medRxiv : the preprint server for health sciences (2024)
Mitchell R Lucas, Janice C Atkins, Luke C Pilling, Jeremy D Shearman, David Melzer
HFE genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank. BMJ open 14 (3) (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, David Melzer, Luke C Pilling
SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients. International journal of molecular sciences 25 (8) (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, David Melzer, Luke C Pilling
SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients. International journal of molecular sciences 25 (8) (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, João Delgado, Chia-Ling Kuo, David Melzer, Luke C Pilling
Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone. The pharmacogenomics journal 24 (3) (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, João Delgado, Chia-Ling Kuo, David Melzer, Luke C Pilling
Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone. The pharmacogenomics journal 24 (3) (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, João Delgado, Chia-Ling Kuo, David Melzer, Luke C Pilling
Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone. The pharmacogenomics journal 24 (3) (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Chia-Ling Kuo, Peiran Liu, Zhiduo Chen, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
A proteomic signature of healthspan. medRxiv : the preprint server for health sciences (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, João Delgado, Chia-Ling Kuo, David Melzer, Luke C Pilling
Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone. The pharmacogenomics journal 24 (3) (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, David Melzer, Luke C Pilling
SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients. International journal of molecular sciences 25 (8) (2024)
Deniz Türkmen, Jack Bowden, Jane A H Masoli, João Delgado, Chia-Ling Kuo, David Melzer, Luke C Pilling
Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone. The pharmacogenomics journal 24 (3) (2024)
Chia-Ling Kuo, Peiran Liu, Zhiduo Chen, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
A proteomic signature of healthspan. medRxiv : the preprint server for health sciences (2024)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2024)
Chia-Ling Kuo, Ben Kirk, Meiruo Xiang, Luke C Pilling, George A Kuchel, Richard Kremer, Gustavo Duque
Very Low and High Levels of Vitamin D Are Associated with Shorter Leukocyte Telomere Length in 148,321 UK Biobank Participants. Nutrients 15 (6) (2023)
Lucy R Banfield, Karen M Knapp, Luke C Pilling, David Melzer, Janice C Atkins
Hemochromatosis Genetic Variants and Musculoskeletal Outcomes: 11.5-Year Follow-Up in the UK Biobank Cohort Study. JBMR plus 7 (10) (2023)
Chia-Ling Kuo, Rui Liu, Lucas da Cunha Godoy, Luke C Pilling, Richard H Fortinsky, Doug Brugge
Association between Residential Exposure to Air Pollution and Incident Coronary Heart Disease Is Not Mediated by Leukocyte Telomere Length: A UK Biobank Study. Toxics 11 (6) (2023)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2023)
Chia-Ling Kuo, Ben Kirk, Meiruo Xiang, Luke C Pilling, George A Kuchel, Richard Kremer, Gustavo Duque
Very Low and High Levels of Vitamin D Are Associated with Shorter Leukocyte Telomere Length in 148,321 UK Biobank Participants. Nutrients 15 (6) (2023)
Chia-Ling Kuo, Rui Liu, Lucas da Cunha Godoy, Luke C Pilling, Richard H Fortinsky, Doug Brugge
Association between Residential Exposure to Air Pollution and Incident Coronary Heart Disease Is Not Mediated by Leukocyte Telomere Length: A UK Biobank Study. Toxics 11 (6) (2023)
Chia-Ling Kuo, Ben Kirk, Meiruo Xiang, Luke C Pilling, George A Kuchel, Richard Kremer, Gustavo Duque
Very Low and High Levels of Vitamin D Are Associated with Shorter Leukocyte Telomere Length in 148,321 UK Biobank Participants. Nutrients 15 (6) (2023)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2023)
Chia-Ling Kuo, Zhiduo Chen, Peiran Liu, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, Breno S Diniz
Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults. medRxiv : the preprint server for health sciences (2023)
Janice C Atkins, Luke C Pilling, Suzy V Torti, Frank M Torti, George A Kuchel, David Melzer
Hereditary Hemochromatosis Variant Associations with Incident Nonliver Malignancies: 11-Year Follow-up in UK Biobank. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 31 (9) (2022)
Deniz Türkmen, Jane A H Masoli, Chia-Ling Kuo, Jack Bowden, David Melzer, Luke C Pilling
Statin treatment effectiveness and the SLCO1B1*5 reduced function genotype: Long-term outcomes in women and men. British journal of clinical pharmacology 88 (7) (2022)
Luke C Pilling, Janice C Atkins, David Melzer
Genetic modifiers of penetrance to liver endpoints in HFE hemochromatosis: Associations in a large community cohort. Hepatology (Baltimore, Md.) 76 (6) (2022)
Deniz Türkmen, Jane A H Masoli, João Delgado, Chia-Ling Kuo, Jack Bowden, David Melzer, Luke C Pilling
Calcium-channel blockers: Clinical outcome associations with reported pharmacogenetics variants in 32 000 patients. British journal of clinical pharmacology (2022)
Janice C Atkins, Juulia Jylhävä, Nancy L Pedersen, Patrik K Magnusson, Yi Lu, Yunzhang Wang, Sara Hägg, David Melzer, Dylan M Williams, Luke C Pilling
A genome-wide association study of the frailty index highlights brain pathways in ageing. Aging cell 20 (9) (2021)
Chia-Ling Kuo, Luke C Pilling, Janice C Atkins, Richard H Fortinsky, George A Kuchel, David Melzer
APOE e4 genotypes increase risk of delirium during COVID-19 related hospitalizations: evidence from a large United Kingdom cohort. The journals of gerontology. Series A, Biological sciences and medical sciences (2021)
Jack Bowden, Luke C Pilling, Deniz Türkmen, Chia-Ling Kuo, David Melzer
The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research. PLoS genetics 17 (9) (2021)
Chia-Ling Kuo, Luke C Pilling, Janice C Atkins, Jane A H Masoli, João C Delgado, Christopher Tignanelli, George A Kuchel, David Melzer, Kenneth B Beckman, Morgan E Levine
Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants. The journals of gerontology. Series A, Biological sciences and medical sciences 76 (8) (2021)
Luke C Pilling, Deniz Türkmen, Hannah Fullalove, Janice C Atkins, João C Delgado, Chia-Ling Kuo, George A Kuchel, Luigi Ferrucci, Jack Bowden, Jane A H Masoli, David Melzer
Analysis of CYP2C19 genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study. BMJ open 11 (12) (2021)
Garan Jones, Katerina Trajanoska, Adam J Santanasto, Najada Stringa, Chia-Ling Kuo, Janice C Atkins, Joshua R Lewis, ThuyVy Duong, Shengjun Hong, Mary L Biggs, Jian'an Luan, Chloe Sarnowski, Kathryn L Lunetta, Toshiko Tanaka, Mary K Wojczynski, Ryan K Cvejkus, Maria Nethander, Sahar Ghasemi, Jingyun Yang, M Carola Zillikens, Stefan Walter, Kamil Sicinski, Erika Kague, Cheryl L Ackert-Bicknell, Dan E Arking, B Gwen Windham, Eric Boerwinkle, Megan L Grove, Mariaelisa Graff, Dominik Spira, Ilja Demuth, Nathalie van der Velde, Lisette C P G M de Groot, Bruce M Psaty, Michelle C Odden, Alison E Fohner, Claudia Langenberg, Nicholas J Wareham, Stefania Bandinelli, Natasja M van Schoor, Martijn Huisman, Qihua Tan, Joseph Zmuda, Dan Mellström, Magnus Karlsson, David A Bennett, Aron S Buchman, Philip Lawrence De Jager, Andre G Uitterlinden, Linus Völker, Thomas Kocher, Alexander Teumer, Leocadio Rodriguéz-Mañas, Francisco J García, José A Carnicero, Pamela Herd, Lars Bertram, Claes Ohlsson, Joanne M Murabito, David Melzer, George A Kuchel, Luigi Ferruci, David Karasik, Fernando Rivadeneira, Douglas P Kiel, Luke C Pilling
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nature communications 12 (1) (2021)
Luke C Pilling, Lindsay C Jones, Jane A H Masoli, João C Delgado, Janice L Atkins, Jack Bowden, Richard H Fortinsky, George A Kuchel, David Melzer
Low Vitamin D Levels and Risk of Incident Delirium in 351,000 Older UK Biobank Participants. Journal of the American Geriatrics Society 69 (2) (2020)
Chia-Ling Kuo, Luke C Pilling, Janice C Atkins, Jane Masoli, João C Delgado, Christopher J Tignanelli, George A Kuchel, David Melzer, Kenneth B Beckman, Morgan E Levine
COVID-19 severity is predicted by earlier evidence of accelerated aging. medRxiv : the preprint server for health sciences (2020)
Chia-Ling Kuo, Luke C Pilling, Zuyun Liu, Janice C Atkins, Morgan E Levine
Genetic associations for two biological age measures point to distinct aging phenotypes. medRxiv : the preprint server for health sciences (2020)
Kirsty Bowman, Lindsay Jones, Luke C Pilling, João C Delgado, George A Kuchel, Luigi Ferrucci, Richard H Fortinsky, David Melzer
Vitamin D levels and risk of delirium: A mendelian randomization study in the UK Biobank. Neurology 92 (12) (2019)
Luke C Pilling, Janice C Atkins, George A Kuchel, Luigi Ferrucci, David Melzer
Red cell distribution width and common disease onsets in 240,477 healthy volunteers followed for up to 9 years. PloS one 13 (9) (2018)
Luke C Pilling, Janice C Atkins, Michael O Duff, Robin N Beaumont, Samuel E Jones, Jessica Tyrrell, Chia-Ling Kuo, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Andrew R Wood, Anna Murray, Michael N Weedon, Lorna W Harries, George A Kuchel, Luigi Ferrucci, Timothy M Frayling, David Melzer
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. PloS one 12 (9) (2017)
Luke C Pilling, R Joehanes, T Kacprowski, M Peters, R Jansen, D Karasik, D P Kiel, L W Harries, A Teumer, J Powell, D Levy, H Lin, K Lunetta, P Munson, S Bandinelli, W Henley, D Hernandez, A Singleton, T Tanaka, G van Grootheest, A Hofman, A G Uitterlinden, R Biffar, S Gläser, G Homuth, C Malsch, U Völker, B Penninx, J B J van Meurs, L Ferrucci, T Kocher, J Murabito, D Melzer
Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. Physiological genomics 48 (1) (2015)