LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription.

Bingqiu XiuYayun ChiLei LiuWeiru ChiQi ZhangJiajian ChenRong GuoJing SiLun LiJingyan XueZhi-Ming ShaoZhao-Hui WuShenglin HuangJiong Wu

Published in: Molecular cancer (2019)

Our findings uncover a key role of LINC02273-hnRNPL-AGR2 axis in breast cancer metastasis and provide potential novel therapeutic targets for metastatic breast cancer intervention.

Keyphrases

metastatic breast cancer
long noncoding rna
long non coding rna
cell proliferation
randomized controlled trial
transcription factor
young adults
risk assessment