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Wen-Shen-Tong-Luo-Zhi-Tong Decoction regulates bone-fat balance in osteoporosis by adipocyte-derived exosomes.

Lining WangYa-Lan PanMengmig LiuJie SunLi YunPengcheng TuChengjie WuZiceng YuZhitao HanMuzhe LiYang GuoJianchao Gui
Published in: Pharmaceutical biology (2023)
WSTLZT can exert anti-OP effect through SPRY2 via the MAKP signalling by miR-122-5p carried by adipocyte-derived exosomes.
Keyphrases
  • adipose tissue
  • fatty acid
  • mesenchymal stem cells
  • bone mineral density
  • insulin resistance
  • stem cells
  • postmenopausal women
  • type diabetes
  • soft tissue
  • skeletal muscle
  • body composition
  • bone marrow