Association between TNF-α polymorphisms and gestational diabetes mellitus: a meta-analysis and trial sequential analysis.

Jing LiuGuang SongGe ZhaoTao Meng

Published in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2020)

For Asian populations, TNF-α rs1800629 is a risk factor for GDM. There was no association between two TNF-α polymorphisms (rs361525 and rs1799724) and GDM under all genetic models. More multi-ethnic and larger sample size studies are needed to confirm these null associations.

Keyphrases

rheumatoid arthritis
pregnant women
clinical trial
study protocol
phase iii
randomized controlled trial
phase ii
gene expression
copy number