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Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology?

Francesco GrussuTorben SchneiderCarmen TurRichard L YatesMohamed TachrountAndrada IanuşMarios C YiannakasJia NewcombeHui ZhangDaniel C AlexanderGabriele C DeLucaClaudia A M Gandini Wheeler-Kingshott
Published in: Annals of clinical and translational neurology (2017)
Neurite orientation dispersion detects a previously undescribed and potentially relevant layer of microstructural complexity of multiple sclerosis spinal cord pathology. Clinically feasible techniques such as NODDI may play a key role in clinical trial and practice settings, as they provide histologically meaningful dispersion indices.
Keyphrases
  • multiple sclerosis
  • spinal cord
  • white matter
  • clinical trial
  • spinal cord injury
  • neuropathic pain
  • primary care
  • healthcare
  • study protocol
  • double blind
  • randomized controlled trial
  • phase iii