Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia: CARE-FH Protocol.
Laney K JonesMarc S WilliamsIlene G LaddDylan CawleyShuping GeJing HaoDina HassenYirui HuH Lester KirchnerMaria KobylinskiMichael G LeskoMatthew C NelsonAlanna Kulchak RahmDavid D RolstonKatrina M RomagnoliTyler J SchubertTimothy C ShueyAmy C SturmSamuel S GiddingPublished in: Journal of personalized medicine (2022)
The Collaborative Approach to Reach Everyone with Familial Hypercholesterolemia (CARE-FH) study aims to improve diagnostic evaluation rates for FH at Geisinger, an integrated health delivery system. This clinical trial relies upon implementation science to transition the initial evaluation for FH into primary care, attempting to identify individuals prior to the onset of atherosclerotic cardiovascular disease events. The protocol for the CARE-FH study of this paper is available online. The first phase of the project focuses on trial design, including the development of implementation strategies to deploy evidence-based guidelines. The second phase will study the intervention, rolled out regionally to internal medicine, community medicine, and pediatric care clinicians using a stepped-wedge design, and analyzing data on diagnostic evaluation rates, and implementation, service, and health outcomes.
Keyphrases
- healthcare
- quality improvement
- primary care
- palliative care
- clinical trial
- cardiovascular disease
- randomized controlled trial
- mental health
- public health
- study protocol
- pain management
- type diabetes
- climate change
- machine learning
- health information
- coronary artery disease
- chronic pain
- affordable care act
- risk assessment
- general practice
- human health
- data analysis