Combined association of obesity and other cardiometabolic diseases with severe COVID-19 outcomes: a nationwide cross-sectional study of 21 773 Brazilian adult and elderly inpatients.
Natanael Jesus da SilvaRita de Cássia Ribeiro-SilvaAndrêa Jacqueline Fortes FerreiraCamila Silveira Silva TeixeiraAline Santos RochaFlávia Jôse Oliveira AlvesIla Rocha FalcãoElizabete de Jesus PintoCarlos Antônio de Souza Teles SantosRosemeire Leovigildo FiacconeMaria Yury Travassos IchiharaEnny Santos da PaixãoMauricio L BarretoPublished in: BMJ open (2021)
The combined association of obesity, diabetes and/or CVD with severe COVID-19 outcomes may be stronger in adults than in elders. Obesity alone and combined with DM and/or CVD had more impact on the risk of COVID-19 severity than DM and/or CVD in both age groups. The study also supports an independent relationship of obesity with severe outcomes, including a dose-response association between degrees of obesity and death in adults.