Development and external validation of prediction models to predict implantable cardioverter-defibrillator efficacy in primary prevention of sudden cardiac death.
Tom E VerstraelenMarit van BarreveldPascal F H M van DesselLucas V A BoersmaPeter-Paul P H M DelnoyAnton E TuinenburgDominic A M J TheunsPepijn H van der VoortGerardus P KimmanErik BuskensMichiel HullemanCornelis P AllaartSipke StrikwerdaMarcoen F ScholtenMathias MeineRené AbelsAlexander H MaassMehran FirouziJos W M G WiddershovenJan EldersMarco W F van GentMuchtiar KhanKevin VernooyRobert W GraussRaymond TukkieLieselot van ErvenHan A M SpierenburgMarc A BrouwerGerard L BartelsNick R BijsterveldAlida E Borger van der BurgMattheus W VetRichard DerksenReinoud E KnopsFrank A L E BrackeMarkus HardenChristian SticherlingRik WillemsTim FriedeMarkus ZabelMarcel G W DijkgraafAeilko H ZwindermanArthur A M WildePublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2021)
Although this cohort study was specifically designed to develop prediction models, risk stratification still remains challenging and no large group with insufficient benefit of ICD implantation was found. However, the prediction models have some clinical utility as we present several scenarios where ICD implantation might be postponed.
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