Tim Friede

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 144

Top Venues

Biometrical journal. Biometrische Zeitschrift

Statistics in medicine

Statistical methods in medical research

Research synthesis methods

This page only lists publications with an associated author ORCID identifier.

Publications

Stephan von Haehling, Wolfram Döhner, Ruben Evertz, Tania Garfias-Veitl, Carlotta Derad, Monika Diek, Mahir Karakas, Ralf Birkemeyer, Gerasimos Fillippatos, Mitja Lainscak, Javed Butler, Piotr Ponikowski, Michael Böhm, Tim Friede, Stefan D Anker
Ferric carboxymaltose and exercise capacity in heart failure with preserved ejection fraction and iron deficiency: the FAIR-HFpEF trial. European heart journal (2024)
Lisa Derendorf, Stephanie Stock, Dusan Simic, Arim Shukri, Christine Zelenak, Jonas Nagel, Tim Friede, Bea Herbeck Belnap, Christoph Herrmann-Lingen, Susanne S Pedersen, Jan Sørensen, Dirk Müller And On Behalf Of The Escape Consortium
Health economic evaluation of blended collaborative care for older multimorbid heart failure patients: study protocol. Cost effectiveness and resource allocation : C/E 22 (1) (2024)
Amra Hot, Maria Stark, Tim Friede, Annette Kopp-Schneider, Silvia Calderazzo, Maria Reichert, Michael Wolf, Ulrich Wirth, Stefan Schopf, Antonia Zapf
A diagnostic phase III/IV seamless design to investigate the diagnostic accuracy and clinical effectiveness using the example of HEDOS and HEDOS II. Statistical methods in medical research 33 (3) (2024)
Tina Mallon, Josefine Schulze, Judith Dams, Jan Weber, Thomas Asendorf, Silke Böttcher, Uta Sekanina, Franziska Schade, Nils Schneider, Michael Freitag, Christiane Müller, Hans-Helmut König, Friedemann Nauck, Tim Friede, Martin Scherer, Gabriella Marx
Evaluating palliative care case conferences in primary care for patients with advanced non-malignant chronic conditions: a cluster-randomised controlled trial (KOPAL). Age and ageing 53 (5) (2024)
Markus Zabel, Tim Friede
Electrocardiographic risk stratification in patients with a primary prophylactic implantable cardioverter defibrillator: can future arrhythmias correlating with sudden cardiac death be predicted? Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 26 (6) (2024)
Maximilian Bardo, Cynthia Huber, Norbert Benda, Jonas Brugger, Tobias Fellinger, Vaidotas Galaune, Judith Heinz, Harald Heinzl, Andrew C Hooker, Florian Klinglmüller, Franz König, Tim Mathes, Martina Mittlboeck, Martin Posch, Robin Ristl, Tim Friede
Methods for non-proportional hazards in clinical trials: A systematic review. Statistical methods in medical research 33 (6) (2024)
Ari Pelli, Tuomas V Kenttä, Heikki V Huikuri, Cynthia Huber, Simon Schlögl, Markus Zabel, Marek Malik, Rik Willems, Marc A Vos, Markus Harden, Tim Friede, Christian Sticherling, Heikki V Huikuri, null null
Lack of Prognostic Value of T-Wave Alternans for Implantable Cardioverter-Defibrillator Benefit in Primary Prevention. Journal of the American Heart Association 13 (11) (2024)
Omar Ammous, Regina Kampo, Maximilian Wollsching-Strobel, Maximilian Zimmermann, Stefan Andreas, Tim Friede, Doreen Kroppen, Sarah Bettina Stanzel, Susanna Salem, Wolfram Windisch, Tim Mathes
Adherence-enhancing interventions for pharmacological and oxygen therapy in patients with COPD: a systematic review and component network meta-analyses. European respiratory review : an official journal of the European Respiratory Society 33 (173) (2024)
Amra Hot, Maria Stark, Tim Friede, Annette Kopp-Schneider, Silvia Calderazzo, Maria Reichert, Michael Wolf, Ulrich Wirth, Stefan Schopf, Antonia Zapf
A diagnostic phase III/IV seamless design to investigate the diagnostic accuracy and clinical effectiveness using the example of HEDOS and HEDOS II. Statistical methods in medical research 33 (3) (2024)
Ari Pelli, Tuomas V Kenttä, Heikki V Huikuri, Cynthia Huber, Simon Schlögl, Markus Zabel, Marek Malik, Rik Willems, Marc A Vos, Markus Harden, Tim Friede, Christian Sticherling, Heikki V Huikuri, null null
Lack of Prognostic Value of T-Wave Alternans for Implantable Cardioverter-Defibrillator Benefit in Primary Prevention. Journal of the American Heart Association 13 (11) (2024)
Maximilian Bardo, Cynthia Huber, Norbert Benda, Jonas Brugger, Tobias Fellinger, Vaidotas Galaune, Judith Heinz, Harald Heinzl, Andrew C Hooker, Florian Klinglmüller, Franz König, Tim Mathes, Martina Mittlboeck, Martin Posch, Robin Ristl, Tim Friede
Methods for non-proportional hazards in clinical trials: A systematic review. Statistical methods in medical research (2024)
Ari Pelli, Tuomas V Kenttä, Heikki V Huikuri, Cynthia Huber, Simon Schlögl, Markus Zabel, Marek Malik, Rik Willems, Marc A Vos, Markus Harden, Tim Friede, Christian Sticherling, Heikki V Huikuri, null null
Lack of Prognostic Value of T-Wave Alternans for Implantable Cardioverter-Defibrillator Benefit in Primary Prevention. Journal of the American Heart Association (2024)
Christian Röver, Tim Friede
Investigating the Heterogeneity of "Study Twins". Biometrical journal. Biometrische Zeitschrift 66 (6) (2024)
Ari Pelli, Tuomas V Kenttä, Heikki V Huikuri, Cynthia Huber, Simon Schlögl, Markus Zabel, Marek Malik, Rik Willems, Marc A Vos, Markus Harden, Tim Friede, Christian Sticherling, Heikki V Huikuri, null null
Lack of Prognostic Value of T-Wave Alternans for Implantable Cardioverter-Defibrillator Benefit in Primary Prevention. Journal of the American Heart Association 13 (11) (2024)
Maximilian Bardo, Cynthia Huber, Norbert Benda, Jonas Brugger, Tobias Fellinger, Vaidotas Galaune, Judith Heinz, Harald Heinzl, Andrew C Hooker, Florian Klinglmüller, Franz König, Tim Mathes, Martina Mittlboeck, Martin Posch, Robin Ristl, Tim Friede
Methods for non-proportional hazards in clinical trials: A systematic review. Statistical methods in medical research 33 (6) (2024)
Lisa Derendorf, Stephanie Stock, Dusan Simic, Arim Shukri, Christine Zelenak, Jonas Nagel, Tim Friede, Bea Herbeck Belnap, Christoph Herrmann-Lingen, Susanne S Pedersen, Jan Sørensen, Dirk Müller And On Behalf Of The Escape Consortium
Health economic evaluation of blended collaborative care for older multimorbid heart failure patients: study protocol. Cost effectiveness and resource allocation : C/E 22 (1) (2024)
Amra Hot, Maria Stark, Tim Friede, Annette Kopp-Schneider, Silvia Calderazzo, Maria Reichert, Michael Wolf, Ulrich Wirth, Stefan Schopf, Antonia Zapf
A diagnostic phase III/IV seamless design to investigate the diagnostic accuracy and clinical effectiveness using the example of HEDOS and HEDOS II. Statistical methods in medical research 33 (3) (2024)
Omar Ammous, Regina Kampo, Maximilian Wollsching-Strobel, Maximilian Zimmermann, Stefan Andreas, Tim Friede, Doreen Kroppen, Sarah Bettina Stanzel, Susanna Salem, Wolfram Windisch, Tim Mathes
Adherence-enhancing interventions for pharmacological and oxygen therapy in patients with COPD: a systematic review and component network meta-analyses. European respiratory review : an official journal of the European Respiratory Society 33 (173) (2024)
Ari Pelli, Tuomas V Kenttä, Heikki V Huikuri, Cynthia Huber, Simon Schlögl, Markus Zabel, Marek Malik, Rik Willems, Marc A Vos, Markus Harden, Tim Friede, Christian Sticherling, Heikki V Huikuri, null null
Lack of Prognostic Value of T-Wave Alternans for Implantable Cardioverter-Defibrillator Benefit in Primary Prevention. Journal of the American Heart Association 13 (11) (2024)
Oliver Gross, Jan Boeckhaus, Lutz T Weber, Hiddo J Lambers Heerspink, James F Simon, Rees Ahmed, Christoph Gerst, Ulrike Duerr, Florian Walker, Ralf Tostmann, Jürgen Helm, Thomas Asendorf, Tim Friede
Protocol and rationale for a randomized controlled SGLT2 inhibitor trial in pediatric and young adult populations with chronic kidney disease: DOUBLE PRO-TECT Alport. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2024)
Markus Zabel, Tim Friede
Electrocardiographic Risk Stratification in Primary Prophylactic Implantable Cardioverter Defibrillator Patients: Can Future Arrhythmias Correlating with Sudden Cardiac Death Be Predicted? Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)
Richard St John Nicholas, Roberta Magliozzi, Damiano Marastoni, Owain Howell, Federico Roncaroli, Paolo Muraro, Richard Reynolds, Tim Friede
High Levels of Perivascular Inflammation and Active Demyelinating Lesions at Time of Death Associated with Rapidly Progressive Multiple Sclerosis Disease Course: A Retrospective Postmortem Cohort Study. Annals of neurology 95 (4) (2024)
Tina Mallon, Josefine Schulze, Judith Dams, Jan Weber, Thomas Asendorf, Silke Böttcher, Uta Sekanina, Franziska Schade, Nils Schneider, Michael Freitag, Christiane Müller, Hans-Helmut König, Friedemann Nauck, Tim Friede, Martin Scherer, Gabriella Marx
Evaluating palliative care case conferences in primary care for patients with advanced non-malignant chronic conditions: a cluster-randomised controlled trial (KOPAL). Age and ageing 53 (5) (2024)
Maximilian Bardo, Cynthia Huber, Norbert Benda, Jonas Brugger, Tobias Fellinger, Vaidotas Galaune, Judith Heinz, Harald Heinzl, Andrew C Hooker, Florian Klinglmüller, Franz König, Tim Mathes, Martina Mittlboeck, Martin Posch, Robin Ristl, Tim Friede
Methods for non-proportional hazards in clinical trials: A systematic review. Statistical methods in medical research 33 (6) (2024)
Tina Mallon, Josefine Schulze, Judith Dams, Jan Weber, Thomas Asendorf, Silke Böttcher, Uta Sekanina, Franziska Schade, Nils Schneider, Michael Freitag, Christiane Müller, Hans-Helmut König, Friedemann Nauck, Tim Friede, Martin Scherer, Gabriella Marx
Evaluating palliative care case conferences in primary care for patients with advanced non-malignant chronic conditions: a cluster-randomised controlled trial (KOPAL). Age and ageing 53 (5) (2024)
Amra Hot, Maria Stark, Tim Friede, Annette Kopp-Schneider, Silvia Calderazzo, Maria Reichert, Michael Wolf, Ulrich Wirth, Stefan Schopf, Antonia Zapf
A diagnostic phase III/IV seamless design to investigate the diagnostic accuracy and clinical effectiveness using the example of HEDOS and HEDOS II. Statistical methods in medical research 33 (3) (2024)
Markus Zabel, Tim Friede
Electrocardiographic risk stratification in patients with a primary prophylactic implantable cardioverter defibrillator: can future arrhythmias correlating with sudden cardiac death be predicted? Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 26 (6) (2024)
Richard St John Nicholas, Roberta Magliozzi, Damiano Marastoni, Owain Howell, Federico Roncaroli, Paolo Muraro, Richard Reynolds, Tim Friede
High Levels of Perivascular Inflammation and Active Demyelinating Lesions at Time of Death Associated with Rapidly Progressive Multiple Sclerosis Disease Course: A Retrospective Postmortem Cohort Study. Annals of neurology 95 (4) (2024)
Amra Hot, Maria Stark, Tim Friede, Annette Kopp-Schneider, Silvia Calderazzo, Maria Reichert, Michael Wolf, Ulrich Wirth, Stefan Schopf, Antonia Zapf
A diagnostic phase III/IV seamless design to investigate the diagnostic accuracy and clinical effectiveness using the example of HEDOS and HEDOS II. Statistical methods in medical research 33 (3) (2024)
Stefan D Anker, Tim Friede, Ralph-Stephan von Bardeleben, Javed Butler, Muhammad-Shahzeb Khan, Monika Diek, Jutta Heinrich, Martin Geyer, Marius Placzek, Roberto Ferrari, William T Abraham, Ottavio Alfieri, Angelo Auricchio, Antoni Bayes-Genis, John G F Cleland, Gerasimos Filippatos, Finn Gustafsson, Wilhelm Haverkamp, Malte Kelm, Karl-Heinz Kuck, Ulf Landmesser, Aldo Pietro Maggioni, Marco Metra, Vlasis Ninios, Mark C Petrie, Tienush Rassaf, Frank Ruschitzka, Ulrich Schäfer, P Christian Schulze, Konstantinos Spargias, Alec Vahanian, Jose Luis Zamorano, Andreas Zeiher, Mahir Karakas, Friedrich Koehler, Mitja Lainscak, Alper Öner, Nikolaos Mezilis, Efstratios K Theofilogiannakos, Ilias Ninios, Michael Chrissoheris, Panagiota Kourkoveli, Konstantinos Papadopoulos, Grzegorz Smolka, Wojciech Wojakowski, Krzysztof Reczuch, Fausto J Pinto, Łukasz Wiewiórka, Zbigniew Kalarus, Marianna Adamo, Evelyn Santiago-Vacas, Tobias F Ruf, Michael Gross, Joern Tongers, Gerd Hasenfuss, Wolfgang Schillinger, Piotr Ponikowski, null null
Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation. The New England journal of medicine (2024)
Michael J Cartwright, Tim Friede, David Lawrence, Emma May, Tobias Mütze, Kit C B Roes
Stakeholders' Perspectives on Current Issues in Data Monitoring Committees. Biometrical journal. Biometrische Zeitschrift 66 (7) (2024)
Markus Zabel, Tim Friede
Electrocardiographic risk stratification in patients with a primary prophylactic implantable cardioverter defibrillator: can future arrhythmias correlating with sudden cardiac death be predicted? Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 26 (6) (2024)
Ari Pelli, Tuomas V Kenttä, Heikki V Huikuri, Cynthia Huber, Simon Schlögl, Markus Zabel, Marek Malik, Rik Willems, Marc A Vos, Markus Harden, Tim Friede, Christian Sticherling, Heikki V Huikuri, null null
Lack of Prognostic Value of T-Wave Alternans for Implantable Cardioverter-Defibrillator Benefit in Primary Prevention. Journal of the American Heart Association 13 (11) (2024)
Lisa Derendorf, Stephanie Stock, Dusan Simic, Arim Shukri, Christine Zelenak, Jonas Nagel, Tim Friede, Bea Herbeck Belnap, Christoph Herrmann-Lingen, Susanne S Pedersen, Jan Sørensen, Dirk Müller And On Behalf Of The Escape Consortium
Health economic evaluation of blended collaborative care for older multimorbid heart failure patients: study protocol. Cost effectiveness and resource allocation : C/E 22 (1) (2024)
Maximilian Bardo, Cynthia Huber, Norbert Benda, Jonas Brugger, Tobias Fellinger, Vaidotas Galaune, Judith Heinz, Harald Heinzl, Andrew C Hooker, Florian Klinglmüller, Franz König, Tim Mathes, Martina Mittlboeck, Martin Posch, Robin Ristl, Tim Friede
Methods for non-proportional hazards in clinical trials: A systematic review. Statistical methods in medical research 33 (6) (2024)
Amra Hot, Maria Stark, Tim Friede, Annette Kopp-Schneider, Silvia Calderazzo, Maria Reichert, Michael Wolf, Ulrich Wirth, Stefan Schopf, Antonia Zapf
A diagnostic phase III/IV seamless design to investigate the diagnostic accuracy and clinical effectiveness using the example of HEDOS and HEDOS II. Statistical methods in medical research (2024)
Tina Mallon, Josefine Schulze, Judith Dams, Jan Weber, Thomas Asendorf, Silke Böttcher, Uta Sekanina, Franziska Schade, Nils Schneider, Michael Freitag, Christiane Müller, Hans-Helmut König, Friedemann Nauck, Tim Friede, Martin Scherer, Gabriella Marx
Evaluating palliative care case conferences in primary care for patients with advanced non-malignant chronic conditions: a cluster-randomised controlled trial (KOPAL). Age and ageing 53 (5) (2024)
Markus Zabel, Tim Friede
Electrocardiographic risk stratification in patients with a primary prophylactic implantable cardioverter defibrillator: can future arrhythmias correlating with sudden cardiac death be predicted? Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 26 (6) (2024)
Ana Mazur, Britta Tetzlaff, Tina Mallon, Berit Hesjedal-Streller, Vivien Wei, Martin Scherer, Sascha Köpke, Katrin Balzer, Linda Steyer, Tim Friede, Sebastian Pfeiffer, Eva Hummers, Christiane Müller
Cluster randomised trial of a complex interprofessional intervention (interprof ACT) to reduce hospital admission of nursing home residents. Age and ageing 52 (3) (2023)
Andreas Leha, Cynthia Huber, Tim Friede, Timm Bauer, Andreas Beckmann, Raffi Bekeredjian, Sabine Bleiziffer, Eva Herrmann, Helge Möllmann, Thomas Walther, Friedhelm Beyersdorf, Christian Hamm, Arnaud Künzi, Stephan Windecker, Stefan Stortecky, Ingo Kutschka, Gerd Hasenfuß, Stephan Ensminger, Christian Frerker, Tim Seidler
Challenges in developing and validating machine learning models for TAVI mortality risk prediction: reply. European heart journal. Digital health 5 (1) (2023)
Ahmed Abdelhak, Kai Antweiler, Markus C Kowarik, Makbule Senel, Joachim Havla, Uwe K Zettl, Ingo Kleiter, Thomas Skripuletz, Axel Haarmann, Alexander Stahmann, Andre Huss, Stefan Gingele, Markus Krumbholz, Pascal Benkert, Jens Kuhle, Tim Friede, Albert C Ludolph, Ulf Ziemann, Tania Kümpfel, Hayrettin Tumani
Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis. Annals of clinical and translational neurology 11 (2) (2023)
Louisa-Kristin Muntendorf, Katrin Balzer, Tim Friede, Eva Hummers, Hans-Helmut König, Christiane A Mueller, Martin Scherer, Linda Steyer, Britta Tetzlaff, Sebastian Pfeiffer, Alexander Konnopka, null null
Cost-Effectiveness of Inter-Professional Collaboration to Reduce Hospitalisations in Nursing Home Residents: Results from the German Interprof ACT Trial. International journal of integrated care 23 (2) (2023)
Roland G Gera, Tim Friede
Blinded sample size recalculation in multiple composite population designs with normal data and baseline adjustments. Biometrical journal. Biometrische Zeitschrift (2023)
Ahmed Abdelhak, Kai Antweiler, Markus C Kowarik, Makbule Senel, Joachim Havla, Uwe K Zettl, Ingo Kleiter, Thomas Skripuletz, Axel Haarmann, Alexander Stahmann, Andre Huss, Stefan Gingele, Markus Krumbholz, Pascal Benkert, Jens Kuhle, Tim Friede, Albert C Ludolph, Ulf Ziemann, Tania Kümpfel, Hayrettin Tumani
Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis. Annals of clinical and translational neurology 11 (2) (2023)
Richard Nicholas, Jeff Rodgers, James Witts, Annalaura Lerede, Tim Friede, Jan Hillert, Lars Forsberg, Anna Glaser, Ali Manouchehrinia, Ryan Ramanujam, Tim Spelman, Pernilla Klyve, Jiri Drahota, Dana Horakova, Hanna Joensen, Luigi Pontieri, Melinda Magyari, David Ellenberger, Alexander Stahmann, Helmut Butzkueven, Anneke Van Der Walt, Vladimir Bezlyak, Carol Lines, Rodden M Middleton
The impact of healthcare systems on the clinical diagnosis and disease-modifying treatment usage in relapse-onset multiple sclerosis: a real-world perspective in five registries across Europe. Therapeutic advances in neurological disorders 16 (2023)
Louisa-Kristin Muntendorf, Katrin Balzer, Tim Friede, Eva Hummers, Hans-Helmut König, Christiane A Mueller, Martin Scherer, Linda Steyer, Britta Tetzlaff, Sebastian Pfeiffer, Alexander Konnopka, null null
Cost-Effectiveness of Inter-Professional Collaboration to Reduce Hospitalisations in Nursing Home Residents: Results from the German Interprof ACT Trial. International journal of integrated care 23 (2) (2023)
Louisa-Kristin Muntendorf, Katrin Balzer, Tim Friede, Eva Hummers, Hans-Helmut König, Christiane A Mueller, Martin Scherer, Linda Steyer, Britta Tetzlaff, Sebastian Pfeiffer, Alexander Konnopka, null null
Cost-Effectiveness of Inter-Professional Collaboration to Reduce Hospitalisations in Nursing Home Residents: Results from the German Interprof ACT Trial. International journal of integrated care 23 (2) (2023)
Andreas Leha, Cynthia Huber, Tim Friede, Timm Bauer, Andreas Beckmann, Raffi Bekeredjian, Sabine Bleiziffer, Eva Herrmann, Helge Möllmann, Thomas Walther, Friedhelm Beyersdorf, Christian Hamm, Arnaud Künzi, Stephan Windecker, Stefan Stortecky, Ingo Kutschka, Gerd Hasenfuß, Stephan Ensminger, Christian Frerker, Tim Seidler
Challenges in developing and validating machine learning models for TAVI mortality risk prediction: reply. European heart journal. Digital health 5 (1) (2023)
Olympia Papachristofi, Björn Bornkamp, Melanie Wright, Tim Friede
Interim decision making in seamless trial designs: An application in an adaptive dose-finding study in a rare kidney disease. Pharmaceutical statistics (2023)
Christian Röver, Sibylle Sturtz, Jona Lilienthal, Ralf Bender, Tim Friede
Summarizing empirical information on between-study heterogeneity for Bayesian random-effects meta-analysis. Statistics in medicine (2023)
Ahmed Abdelhak, Kai Antweiler, Markus C Kowarik, Makbule Senel, Joachim Havla, Uwe K Zettl, Ingo Kleiter, Thomas Skripuletz, Axel Haarmann, Alexander Stahmann, Andre Huss, Stefan Gingele, Markus Krumbholz, Pascal Benkert, Jens Kuhle, Tim Friede, Albert C Ludolph, Ulf Ziemann, Tania Kümpfel, Hayrettin Tumani
Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis. Annals of clinical and translational neurology 11 (2) (2023)
Charlotte Schubert, Lea Steinberg, Julia Peper, Caren Ramien, Kerstin Hellwig, Sascha Köpke, Alessandra Solari, Andrea Giordano, Stefan M Gold, Tim Friede, Christoph Heesen, Anne Christin Rahn
Postpartum relapse risk in multiple sclerosis: a systematic review and meta-analysis. Journal of neurology, neurosurgery, and psychiatry (2023)
Christian Röver, David Rindskopf, Tim Friede
How trace plots help interpret meta-analysis results. Research synthesis methods (2023)
Jona Lilienthal, Sibylle Sturtz, Christoph Schürmann, Matthias Maiworm, Christian Röver, Tim Friede, Ralf Bender
Bayesian random-effects meta-analysis with empirical heterogeneity priors for application in health technology assessment with very few studies. Research synthesis methods 15 (2) (2023)
Britta Tetzlaff, Martin Scherer, Katrin Balzer, Linda Steyer, Sascha Köpke, Tim Friede, Indre Maurer, Clarissa E Weber, Hans-Helmut König, A Konnopka, Thomas Ruppel, Ana Mazur, Eva Hummers, Christiane A Mueller
Development of an interprofessional person-centred care concept for persons with care needs living in their own homes ( interprof HOME): study protocol for a mixed-methods study. BMJ open 13 (7) (2023)
Matthias Schmid, Tim Friede, Nadja Klein, Leonie Weinhold
Accounting for time dependency in meta-analyses of concordance probability estimates. Research synthesis methods (2023)
Christian Röver, David Rindskopf, Tim Friede
How trace plots help interpret meta-analysis results. Research synthesis methods 15 (3) (2023)
Richard St John Nicholas, Roberta Magliozzi, Damiano Marastoni, Owain Howell, Federico Roncaroli, Paolo Muraro, Richard Reynolds, Tim Friede
High levels of perivascular inflammation and active demyelinating lesions at time of death associated with rapidly progressive multiple sclerosis disease course: a retrospective post-mortem cohort study. Annals of neurology (2023)
Suleman Aktaa, Stylianos Tzeis, Chris P Gale, Michael J Ackerman, Elena Arbelo, Elijah R Behr, Lia Crotti, Andre d'Avila, Christian De Chillou, Thomas Deneke, Marcio Jansen de Oliveira Figueiredo, Tim Friede, Christophe Leclercq, Josè Luis Merino, Christopher Semsarian, Axel Verstrael, Katja Zeppenfeld, Jacob Tfelt Hansen, Tobias Reichlin
European Society of Cardiology quality indicators for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 25 (1) (2023)
Ahmed Abdelhak, Kai Antweiler, Markus C Kowarik, Makbule Senel, Joachim Havla, Uwe K Zettl, Ingo Kleiter, Thomas Skripuletz, Axel Haarmann, Alexander Stahmann, Andre Huss, Stefan Gingele, Markus Krumbholz, Pascal Benkert, Jens Kuhle, Tim Friede, Albert C Ludolph, Ulf Ziemann, Tania Kümpfel, Hayrettin Tumani
Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis. Annals of clinical and translational neurology 11 (2) (2023)
Jona Lilienthal, Sibylle Sturtz, Christoph Schürmann, Matthias Maiworm, Christian Röver, Tim Friede, Ralf Bender
Bayesian random-effects meta-analysis with empirical heterogeneity priors for application in health technology assessment with very few studies. Research synthesis methods (2023)
Markus S Anker, Alessia Lena, Eric J Roeland, Jan Porthun, Sebastian Schmitz, Sara Hadzibegovic, Philipp Sikorski, Ursula Wilkenshoff, Ann-Kathrin Fröhlich, Luisa Valentina Ramer, Matthias Rose, Jan Eucker, Tienush Rassaf, Matthias Totzeck, Lorenz H Lehmann, Stephan von Haehling, Andrew J S Coats, Tim Friede, Javed Butler, Stefan D Anker, Hanno Riess, Ulf Landmesser, Lars Bullinger, Ulrich Keller, Johann Ahn
Patient-reported ability to walk 4 m and to wash: New clinical endpoints and predictors of survival in patients with pre-terminal cancer. Journal of cachexia, sarcopenia and muscle (2023)
Ahmed Abdelhak, Kai Antweiler, Markus C Kowarik, Makbule Senel, Joachim Havla, Uwe K Zettl, Ingo Kleiter, Thomas Skripuletz, Axel Haarmann, Alexander Stahmann, Andre Huss, Stefan Gingele, Markus Krumbholz, Pascal Benkert, Jens Kuhle, Tim Friede, Albert C Ludolph, Ulf Ziemann, Tania Kümpfel, Hayrettin Tumani
Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis. Annals of clinical and translational neurology 11 (2) (2023)
Richard St John Nicholas, Roberta Magliozzi, Damiano Marastoni, Owain Howell, Federico Roncaroli, Paolo Muraro, Richard Reynolds, Tim Friede
High Levels of Perivascular Inflammation and Active Demyelinating Lesions at Time of Death Associated with Rapidly Progressive Multiple Sclerosis Disease Course: A Retrospective Postmortem Cohort Study. Annals of neurology (2023)
Eric Samuel Knop, Markus Pauly, Tim Friede, Thilo Welz
The consequences of neglected confounding and interactions in mixed-effects meta-regression: An illustrative example. Research synthesis methods (2023)
Sarah Friedrich, Tim Friede
On the role of benchmarking data sets and simulations in method comparison studies. Biometrical journal. Biometrische Zeitschrift (2023)
Julia Hoffmann, Sabine Hanß, Monika Kraus, Jens Schaller, Christian Schäfer, Dana Stahl, Stefan D Anker, Gabriele Anton, Thomas Bahls, Stefan Blankenberg, Arne Blumentritt, Leif-Hendrik Boldt, Steffen Cordes, Steffen Desch, Wolfram Döhner, Marcus Dörr, Frank Edelmann, Ingo Eitel, Matthias Endres, Stefan Engelhardt, Jeanette Erdmann, Katharina Eulenburg, Volkmar Falk, Stephan B Felix, Derk Frank, Thomas Franke, Norbert Frey, Tim Friede, Lars Geidel, Lisa Germans, Ulrich Grabmaier, Martin Halle, Jörg Hausleiter, Vera Jakobi, Ahmad-Fawad Jebran, Alexander Jobs, Stefan Kääb, Mahir Karakas, Hugo A Katus, Alexandra Klatt, Christoph Knosalla, Joachim Krebser, Ulf Landmesser, Mahsa Lee, Kristin Lehnert, Stephanie Lesser, Katrin Leyh, Roberto Lorbeer, Stephanie Mach-Kolb, Benjamin Meder, Eike Nagel, Christian H Nolte, Abdul Shokor Parwani, Astrid Petersmann, Miriam Puls, Henriette Rau, Maximilian Reiser, Otto Rienhoff, Tabea Scharfe, Mario Schattschneider, Heiko Scheel, Renate B Schnabel, Andreas Schuster, Boris Schmitt, Tim Seidler, Moritz Seiffert, Barbara-Elisabeth Stähli, Adriane Stas, Thomas Stocker, Lukas von Stülpnagel, Holger Thiele, Rolf Wachter, Reza Wakili, Tanja Weis, Kerstin Weitmann, Heinz-Erich Wichmann, Philipp S Wild, Tanja Zeller, Wolfgang U Hoffmann, Elisabeth Maria Zeisberg, Wolfgram-Hubertus Zimmermann, Dagmar Krefting, Titus Kühne, Annette Peters, Gerd Hasenfuss, Steffen Massberg, Thomas Sommer, Stefanie Dimmeler, Thomas Eschenhagen, Matthias Nauck
The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies. Clinical research in cardiology : official journal of the German Cardiac Society (2023)
Christoph Heesen, Thomas Berger, Karin Riemann-Lorenz, Nicole Krause, Tim Friede, Jana Pöttgen, Björn Meyer, Dagmar Lühmann
Mobile health interventions in multiple sclerosis: A systematic review. Multiple sclerosis (Houndmills, Basingstoke, England) (2023)
Jona Lilienthal, Sibylle Sturtz, Christoph Schürmann, Matthias Maiworm, Christian Röver, Tim Friede, Ralf Bender
Bayesian random-effects meta-analysis with empirical heterogeneity priors for application in health technology assessment with very few studies. Research synthesis methods 15 (2) (2023)
Andreas Leha, Cynthia Huber, Tim Friede, Timm Bauer, Andreas Beckmann, Raffi Bekeredjian, Sabine Bleiziffer, Eva Herrmann, Helge Möllmann, Thomas Walther, Friedhelm Beyersdorf, Christian Hamm, Arnaud Künzi, Stephan Windecker, Stefan Stortecky, Ingo Kutschka, Gerd Hasenfuß, Stephan Ensminger, Christian Frerker, Tim Seidler
Challenges in developing and validating machine learning models for TAVI mortality risk prediction: reply. European heart journal. Digital health 5 (1) (2023)
Ahmed Abdelhak, Kai Antweiler, Markus C Kowarik, Makbule Senel, Joachim Havla, Uwe K Zettl, Ingo Kleiter, Thomas Skripuletz, Axel Haarmann, Alexander Stahmann, Andre Huss, Stefan Gingele, Markus Krumbholz, Pascal Benkert, Jens Kuhle, Tim Friede, Albert C Ludolph, Ulf Ziemann, Tania Kümpfel, Hayrettin Tumani
Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis. Annals of clinical and translational neurology (2023)
Louisa-Kristin Muntendorf, Katrin Balzer, Tim Friede, Eva Hummers, Hans-Helmut König, Christiane A Mueller, Martin Scherer, Linda Steyer, Britta Tetzlaff, Sebastian Pfeiffer, Alexander Konnopka, null null
Cost-Effectiveness of Inter-Professional Collaboration to Reduce Hospitalisations in Nursing Home Residents: Results from the German Interprof ACT Trial. International journal of integrated care 23 (2) (2023)
Ankelien Duchow, Judith Bellmann-Strobl, Tim Friede, Orhan Aktas, Klemens Angstwurm, Ilya Ayzenberg, Achim Berthele, Eva Dawin, Daniel Engels, Katinka Fischer, Martina Flaskamp, Katrin Giglhuber, Matthias Grothe, Joachim Havla, Martin W Hümmert, Sven Jarius, Matthias Kaste, Peter Kern, Ingo Kleiter, Luisa Klotz, Mirjam Korporal-Kuhnke, Markus Kraemer, Markus Krumbholz, Tania Kümpfel, Lisa Lohmann, Marius Ringelstein, Paulus Rommer, Patrick Schindler, Charlotte Schubert, Carolin Schwake, Makbule Senel, Florian Then Bergh, Daria Tkachenko, Hayrettin Tumami, Corinna Trebst, Ioannis Vardakas, Annette Walter, Clemens Warnke, Martin S Weber, Jonathan Wickel, Brigitte Wildemann, Alexander Winkelmann, Friedemann Paul, Jan-Patrick Stellmann, Vivien Häußler, null null
Time to disability milestones and annualized relapse rates in NMOSD and MOGAD. Annals of neurology (2023)
Andreas Leha, Cynthia Huber, Tim Friede, Timm Bauer, Andreas Beckmann, Raffi Bekeredjian, Sabine Bleiziffer, Eva Herrmann, Helge Möllmann, Thomas Walther, Friedhelm Beyersdorf, Christian Hamm, Arnaud Künzi, Stephan Windecker, Stefan Stortecky, Ingo Kutschka, Gerd Hasenfuss, Stephan Ensminger, Christian Frerker, Tim Seidler
Development and validation of explainable machine learning models for risk of mortality in transcatheter aortic valve implantation: TAVI risk machine scores. European heart journal. Digital health 4 (3) (2023)
Piotr Ponikowski, Robert J Mentz, Adrian F Hernandez, Javed Butler, Muhammad Shahzeb Khan, Dirk J van Veldhuisen, Bernard Roubert, Nicole Blackman, Tim Friede, Ewa A Jankowska, Stefan D Anker
Efficacy of Ferric carboxymaltose in heart failure with iron deficiency: an individual patient data meta-analysis. European heart journal (2023)
Marius Placzek, Tim Friede
Blinded sample size recalculation in adaptive enrichment designs. Biometrical journal. Biometrische Zeitschrift (2022)
Markus Diefenhardt, Daniel Martin, Ethan Bernard Ludmir, Maximilian Fleischmann, Ralf-Dieter Hofheinz, Michael Ghadimi, Rebekka Kosmala, Bülent Polat, Tim Friede, Bruce D Minsky, Claus Rödel, Emmanouil Fokas
Development and Validation of a Predictive Model for Toxicity of Neoadjuvant Chemoradiotherapy in Rectal Cancer in the CAO/ARO/AIO-04 Phase III Trial. Cancers 14 (18) (2022)
Jakob Richter, Tim Friede, Jörg Rahnenführer
Improving adaptive seamless designs through Bayesian optimization. Biometrical journal. Biometrische Zeitschrift 64 (5) (2022)
Christian Röver, Moreno Ursino, Tim Friede, Sarah Zohar
A straightforward meta-analysis approach for oncology phase I dose-finding studies. Statistics in medicine 41 (20) (2022)
Satoshi Hattori, Sho Komukai, Tim Friede
Sample size calculation for the augmented logrank test in randomized clinical trials. Statistics in medicine 41 (14) (2022)
Thomas Lehnert, Christian Röver, Sascha Köpke, Jordi Río, Declan T Chard, Veronica Andrea Fittipaldo, Tim Friede, Christoph Heesen, Anne Christin Rahn
Immunotherapy for people with clinically isolated syndrome or relapsing-remitting multiple sclerosis: treatment response by demographic, clinical, and biomarker subgroups (PROMISE)-a systematic review protocol. Systematic reviews 11 (1) (2022)
Beate Jahn, Sarah Friedrich, Joachim Behnke, Joachim Engel, Ursula Garczarek, Ralf Münnich, Markus Pauly, Adalbert Wilhelm, Olaf Wolkenhauer, Markus Zwick, Uwe Siebert, Tim Friede
On the role of data, statistics and decisions in a pandemic. Advances in statistical analysis : AStA : a journal of the German Statistical Society 106 (3) (2022)
Sarah Friedrich, Andreas Groll, Katja Ickstadt, Thomas Kneib, Markus Pauly, Jörg Rahnenführer, Tim Friede
Regularization approaches in clinical biostatistics: A review of methods and their applications. Statistical methods in medical research (2022)
Javed Butler, Stefan D Anker, Lars H Lund, Andrew J S Coats, Gerasimos S Filippatos, Tariq Jamal Siddiqi, Tim Friede, Vincent Fabien, Mikhail Kosiborod, Marco Metra, Ileana L Piña, Fausto Pinto, Patrick Rossignol, Peter van der Meer, Cecilia Bahit, Jan Belohlavek, Michael Böhm, Jasper J Brugts, John G F Cleland, Justin Ezekowitz, Antoni Bayés-Genís, Israel Gotsman, Assen Goudev, Irakli Khintibidze, Joann Lindenfeld, Robert J Mentz, Bela Merkely, Eliodoro Castro Montes, Wilfried Mullens, Jose C Nicolau, Aleksandr Parkhomenko, Piotr Ponikowski, Petar M Seferovic, Michele Senni, Evgeny Shlyakhto, Alain Cohen-Solal, Peter Szecsödy, Klaus Jensen, Fabio Dorigotti, Matthew R Weir, Bertram Pitt
Patiromer for the management of hyperkalemia in heart failure with reduced ejection fraction: the DIAMOND trial. European heart journal 43 (41) (2022)
Christian Röver, Tim Friede
Double arcsine transform not appropriate for meta-analysis. Research synthesis methods 13 (5) (2022)
Katerina Hnatkova, Irena Andršová, Tomas Novotny, Annie Britton, Martin Shipley, Bert Vandenberk, David J Sprenkeler, Heikki V Huikuri, Tobias Reichlin, Simon Schlögl, Marc A Vos, Tim Friede, Axel Bauer, Heikki V Huikuri, Rik Willems, Georg Schmidt, Michael R Franz, Christian Sticherling, Markus Zabel, Marek Malik
QRS micro-fragmentation as a mortality predictor. European heart journal 43 (40) (2022)
Stefan Andreas, Christian Röver, Judith Heinz, Christian Taube, Tim Friede
COPD mortality and exacerbations in the placebo group of clinical trials over two decades: a systematic review and meta-regression. ERJ open research 8 (1) (2022)
Jennifer S Graves, Marius Thomas, Jun Li, Anuja R Shah, Alexandra Goodyear, Markus R Lange, Heinz Schmidli, Dieter A Häring, Tim Friede, Jutta Gärtner
Improving pediatric multiple sclerosis interventional phase III study design: a meta-analysis. Therapeutic advances in neurological disorders 15 (2022)
Beate Jahn, Sarah Friedrich, Joachim Behnke, Joachim Engel, Ursula Garczarek, Ralf Münnich, Markus Pauly, Adalbert Wilhelm, Olaf Wolkenhauer, Markus Zwick, Uwe Siebert, Tim Friede
Authors' response: on the role of data, statistics and decisions in a pandemic. Advances in statistical analysis : AStA : a journal of the German Statistical Society 106 (3) (2022)
Gabriella Marx, Tina Mallon, Nadine Janis Pohontsch, Franziska Schade, Judith Dams, Manuel Zimansky, Thomas Asendorf, Silke Böttcher, Christiane A Mueller, Michael Freitag, Eva Hummers, Hendrik van den Bussche, Ingmar Schaefer, Hans-Helmut König, Stephanie Stiel, Nils Schneider, Friedemann Nauck, Tim Friede, Martin Scherer
Effectiveness of a specialist palliative home care nurse-patient consultation followed by an interprofessional telephone case conference compared with usual care among patients with non-oncological palliative care needs: protocol for the multicentre KOPAL cluster-randomised controlled trial. BMJ open 12 (7) (2022)
Ao Huang, Sho Komukai, Tim Friede, Satoshi Hattori
Using clinical trial registries to inform Copas selection model for publication bias in meta-analysis. Research synthesis methods 12 (5) (2021)
Oliver Gross, Onnen Moerer, Thomas Rauen, Jan Böckhaus, Elion Hoxha, Achim Jörres, Matthias Kamm, Amin Elfanish, Wolfram Windisch, Michael Dreher, Juergen Floege, Stefan Kluge, Christian Schmidt-Lauber, Jan-Eric Turner, Samuel Huber, Marylyn Martina Addo, Simone Scheithauer, Tim Friede, Gerald S Braun, Tobias B Huber, Sabine Blaschke
Validation of a Prospective Urinalysis-Based Prediction Model for ICU Resources and Outcome of COVID-19 Disease: A Multicenter Cohort Study. Journal of clinical medicine 10 (14) (2021)
Ewa Anita Jankowska, Bridget-Anne Kirwan, Mikhail Naum Kosiborod, Javed Butler, Stefan D Anker, Theresa McDonagh, Maria Dorobantu, Jarosław Drożdż, Gerasimos S Filippatos, Andre Keren, Irakli Khintibidze, Hans Kragten, Felipe A Martinez, Marco Metra, Davor Milicic, Jose Carlos Nicolau, Marcus Ohlsson, Alexander Parkhomenko, Domingo Pascual Figal, Frank Ruschitzka, David Sim, Hadi Skouri, Peter van der Meer, Basil S Lewis, Josep Comín Colet, Stephan von Haehling, Alain Cohen-Solal, Tabassome Simon, Wolfram Döhner, Henry J Dargie, Michael Motro, Tim Friede, Vincent Fabien, Fabio Dorigotti, Stuart J Pocock, Piotr Ponikowski
The effect of intravenous ferric carboxymaltose on health-related quality of life in iron-deficient patients with acute heart failure: the results of the AFFIRM-AHF study. European heart journal (2021)
Regina Stegherr, Claudia Schmoor, Michael Lübbert, Tim Friede, Jan Beyersmann
Estimating and comparing adverse event probabilities in the presence of varying follow-up times and competing events. Pharmaceutical statistics 20 (6) (2021)
Sarah Friedrich, Stefan Gross, Inke R König, Sandy Engelhardt, Martin Bahls, Judith Heinz, Cynthia Huber, Lars Kaderali, Marcus Kelm, Andreas Leha, Jasmin Rühl, Jens Schaller, Clemens Scherer, Marcus Vollmer, Tim Seidler, Tim Friede
Applications of artificial intelligence/machine learning approaches in cardiovascular medicine: a systematic review with recommendations. European heart journal. Digital health 2 (3) (2021)
Sarah Friedrich, Stefan Gross, Inke R König, Sandy Engelhardt, Martin Bahls, Judith Heinz, Cynthia Huber, Lars Kaderali, Marcus Kelm, Andreas Leha, Jasmin Rühl, Jens Schaller, Clemens Scherer, Marcus Vollmer, Tim Seidler, Tim Friede
Applications of artificial intelligence/machine learning approaches in cardiovascular medicine: a systematic review with recommendations. European heart journal. Digital health 2 (3) (2021)
Tom E Verstraelen, Marit van Barreveld, Pascal F H M van Dessel, Lucas V A Boersma, Peter-Paul P H M Delnoy, Anton E Tuinenburg, Dominic A M J Theuns, Pepijn H van der Voort, Gerardus P Kimman, Erik Buskens, Michiel Hulleman, Cornelis P Allaart, Sipke Strikwerda, Marcoen F Scholten, Mathias Meine, René Abels, Alexander H Maass, Mehran Firouzi, Jos W M G Widdershoven, Jan Elders, Marco W F van Gent, Muchtiar Khan, Kevin Vernooy, Robert W Grauss, Raymond Tukkie, Lieselot van Erven, Han A M Spierenburg, Marc A Brouwer, Gerard L Bartels, Nick R Bijsterveld, Alida E Borger van der Burg, Mattheus W Vet, Richard Derksen, Reinoud E Knops, Frank A L E Bracke, Markus Harden, Christian Sticherling, Rik Willems, Tim Friede, Markus Zabel, Marcel G W Dijkgraaf, Aeilko H Zwinderman, Arthur A M Wilde
Development and external validation of prediction models to predict implantable cardioverter-defibrillator efficacy in primary prevention of sudden cardiac death. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 23 (6) (2021)
Nicole Krause, Karin Riemann-Lorenz, Tanja Steffen, Anne Christin Rahn, Jana Pöttgen, Jan-Patrick Stellmann, Sascha Köpke, Tim Friede, Andrea Icks, Markus Vomhof, Herbert Temmes, Markus van de Loo, Stefan M Gold, Christoph Heesen
Study protocol for a randomised controlled trial of a web-based behavioural lifestyle programme for emPOWERment in early Multiple Sclerosis (POWER@MS1). BMJ open 11 (2) (2021)
Regina Stegherr, Claudia Schmoor, Jan Beyersmann, Kaspar Rufibach, Valentine Jehl, Andreas Brückner, Lewin Eisele, Thomas Künzel, Katrin Kupas, Frank Langer, Friedhelm Leverkus, Anja Loos, Christiane Norenberg, Florian Voss, Tim Friede
Survival analysis for AdVerse events with VarYing follow-up times (SAVVY)-estimation of adverse event risks. Trials 22 (1) (2021)
Alexandra Dopfer-Jablonka, Christian Dopfer, Christine Happle, Andree Shalabi, Martin Wetzke, Eva Hummers, Tim Friede, Stephanie Heinemann, Nele Hillermann, Anne Simmenroth, Frank Müller
Acute respiratory infections in an adult refugee population: an observational study. NPJ primary care respiratory medicine 31 (1) (2021)

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Tim Friede