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Evodiamine derivatives improve cognitive abilities in APPswe/PS1ΔE9 transgenic mouse models of Alzheimer's disease.

Shuo PangCaixian SunShan GaoYajun YangXiandao PanLianfeng Zhang
Published in: Animal models and experimental medicine (2020)
Our study provides insights for developing novel evodiamine derivatives for chemical intervention and treatment of AD.
Keyphrases
  • mouse model
  • randomized controlled trial
  • cognitive decline
  • structure activity relationship
  • replacement therapy