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The study of GSDMB in pathogenesis of psoriasis vulgaris.

Xiaojuan JiHuaqing ChenLing XieShiqi ChenShan HuangQi TanHuifang YangTao YangXiaoying YeZhaolin ZengChunlei WanLongnian Li
Published in: PloS one (2023)
The expression level of GSDMB in psoriasis vulgaris lesion tissue is lower than that of normal skin tissue. The down-regulation of GSDMB expression can inhibit cell proliferation and promote cell apoptosis. GSDMB may play a role in the pathogenesis of psoriasis by affecting the differentiation of keratinocytes and the function of T cells.
Keyphrases
  • cell proliferation
  • poor prognosis
  • atopic dermatitis
  • binding protein
  • wound healing
  • cell cycle
  • long non coding rna
  • pi k akt
  • signaling pathway