Pervasiveness of HLA allele-specific expression loss across tumor types.
Ioan FilipAnqi WangOleksandr KravetsRose OrenbuchJunfei ZhaoTomin E Perea-ChambleeGulam A ManjiEvangelina López de MaturanaNúria MalatsKenneth P OliveRaul Rabadan
Published in: Genome medicine (2023)
Together, our results highlight the prevalence of HLA-I ASE loss and provide initial evidence of its clinical significance in cancer prognosis and immunotherapy treatment.