CRISPR/Cas9-Engineered HLA-Deleted Glomerular Endothelial Cells as a Tool to Predict Pathogenic Non-HLA Antibodies in Kidney Transplant Recipients.
Baptiste LamarthéeCarole BurgerCharlotte LeclaireEmilie LebraudAniela ZablockiLise MorinXavier LebretonBéatrice CharreauRenaud SnanoudjSoëli CharbonnierTifanie BleinMélanie HardyJulien ZuberSimon SatchellMorgan GallazziniFabiola TerziChristophe LegendreJean Luc TaupinMarion RabantClaire TinelDany AnglicheauPublished in: Journal of the American Society of Nephrology : JASN (2022)
The NHADIA identifies non-HLA Abs and strongly predicts graft endothelial injury independent of HLA-DSAs.