Mycoplasma haemohominis as a cause of fever of unknown origin in a traveller.

Candidatus Mycoplasma haemohominis (cMh) is the most human-adapted and lethal hemoplasma. Bats are the common reservoir worldwide. cMh should be suspected in PUO associated with splenomegaly, and hemolytic anaemia or hemophagocytic lymphohistiocytosis, above all in Asia Pacific travellers. Doxycycline can be started preemptively as diagnosis can be retrospectively confirmed.