Efficacy and safety of ipragliflozin and metformin for visceral fat reduction in patients with type 2 diabetes receiving treatment with dipeptidyl peptidase-4 inhibitors in Japan: a study protocol for a prospective, multicentre, blinded-endpoint phase IV randomised controlled trial (PRIME-V study).

Masaya KoshizakaKo IshikawaTakahiro IshikawaKazuki KobayashiMinoru TakemotoTakuro HorikoshiRyota ShimofusaSho TakahashiKengo NagashimaYasunori SatoIchiro TatsunoTakashi TeranoNaotake HashimotoNobuichi KuribayashiDaigaku UchidaKoutaro Yokotenull null

Published in: BMJ open (2017)

UMIN000015170, R000016861 (https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000016861); Pre-results.

Keyphrases

study protocol
adipose tissue
clinical trial
randomized controlled trial
insulin resistance
metabolic syndrome
skeletal muscle
double blind
combination therapy
placebo controlled