Pulmonary epithelial markers in phenotypes of chronic lung allograft dysfunction.
Liran LevySajad MoshkelgoshaElla HusztiSarah HunterBenjamin Renaud-PicardGregory BerraMitsuaki KawashimaJuan Fernandez-CastilloEyal FuchsMilagros DiantiRasheed GhanyShaf KeshavjeeLianne G SingerJussi TikkanenTereza MartinuPublished in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation (2023)
Airway epithelial mucins and cell death markers are enhanced in the BAL of patients with CLAD and can assist in differentiating between CLAD phenotypes and post-CLAD outcomes. Abnormal airway mucin expression and epithelial cell death may be involved in the pathogenesis of CLAD, and therefore their detection may aid in future selection of targeted therapies.