High levels of circulating cell-free DNA are a biomarker of active SLE.

Yalan XuYijun SongJiazhen ChangXiya ZhouQingwei QiXinping TianMengtao LiXiaofeng ZengMengnan XuWenjuan ZhangDavid S CramJuntao Liu

Published in: European journal of clinical investigation (2018)

Our results suggest that in addition to classical SLE serological markers, measurement of circulating plasma cfDNA levels has potential as a useful biomarker for assessing SLE disease activity in patients and monitoring treatment.

Keyphrases

disease activity
systemic lupus erythematosus
rheumatoid arthritis
rheumatoid arthritis patients
ankylosing spondylitis
end stage renal disease
juvenile idiopathic arthritis
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
combination therapy
climate change
replacement therapy