The alteration of the gut microbiome by immunosuppressive agents used in solid organ transplantation.
Caitlin M GibsonLindsey M Childs-KeanZahra NaziruddinCrystal K HowellPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2020)
Some immunosuppressants are associated with changes in gut flora, but the impact on clinical outcomes is unknown. Robust clinical trials delineating the direct effect of immunosuppressants on the gut microbiome as well as the impact on clinical outcomes are warranted.