Pre-transplant CD45RC expression on blood T cells differentiates patients with cancer and rejection after kidney transplantation.
Anne-Sophie GarnierMartin PlanchaisJérémie RiouClément JacqueminLaurence OrdonezJean-Paul Saint-AndréAnne CroueAbdelhadi SaoudiYves DelnesteAnne DevysIsabelle BoutinJean-François SubraAgnès DuveauJean François AugustoPublished in: PloS one (2019)
High frequency of CD45RChigh T cells was associated with AR, while low frequency was associated with cancer. Thus, CD45RC expression on T cells appears as a double-edged sword biomarker of promising interest to assess both cancer and AR risk before kidney transplantation.