The expression level of circ_0073585 is decreased in AML patients. Overexpression of circ_0073585 can inhibit the proliferation and viability of leukemic cells, promote apoptosis, and increase sensitivity of leukemia cells to chemotherapy drugs.
Keyphrases
- cell cycle arrest
- induced apoptosis
- acute myeloid leukemia
- poor prognosis
- cell death
- endoplasmic reticulum stress
- end stage renal disease
- signaling pathway
- oxidative stress
- ejection fraction
- pi k akt
- chronic kidney disease
- cell proliferation
- bone marrow
- peritoneal dialysis
- prognostic factors
- long non coding rna
- allogeneic hematopoietic stem cell transplantation
- patient reported outcomes
- acute lymphoblastic leukemia
- drug induced