Platelet-derived growth factor receptor β-targeted positron emission tomography imaging for the noninvasive monitoring of liver fibrosis.

Zhao LiHao YangXin LiTianshan SheZe TaoYi ZhongTao SuYanru FengQiuxiao ShiLin LiRong TianShisheng WangJingqiu ChengHuawei CaiXiaofeng Lu

Published in: European journal of nuclear medicine and molecular imaging (2024)

PDGFRβ is a reliable biomarker for both human and mouse aHSCs. PDGFRβ-targeted PET imaging could be used for noninvasive monitoring of liver fibrosis in mice and has great potential for clinical translation.

Keyphrases

liver fibrosis
pet imaging
positron emission tomography
growth factor
computed tomography
cancer therapy
endothelial cells
high resolution
pet ct
induced pluripotent stem cells
pluripotent stem cells
high fat diet induced
type diabetes
skeletal muscle
adipose tissue
photodynamic therapy
wild type