HOW Collaborative position paper on the management of thrombocytopenia in pregnancy.
Renee EslickBriony CuttsEileen MerrimanClaire McLintockNolan McDonnellAntonia W ShandLisa ClarkeSara NgIan KandoJennifer CurnowPublished in: The Australian & New Zealand journal of obstetrics & gynaecology (2021)
Thrombocytopenia in pregnancy is a common occurrence, affecting up to 10% of women by the time of birth. These recommendations aim to provide pragmatic guidance on the investigation, diagnosis and management of thrombocytopenia in pregnancy; including safety of neuraxial anaesthesia and precautions required for birth. Management of neonatal thrombocytopenia is also addressed. The authors are clinicians representing haematology, obstetric medicine, maternal-fetal medicine, and anaesthesia. Each author conducted a detailed literature review then worked collaboratively to produce a series of unanimous recommendations. The recommendation strength is limited by the lack of high-quality clinical trial data, and represents level C evidence.
Keyphrases
- pregnancy outcomes
- pregnant women
- clinical trial
- preterm birth
- gestational age
- study protocol
- risk assessment
- palliative care
- clinical practice
- randomized controlled trial
- polycystic ovary syndrome
- open label
- double blind
- metabolic syndrome
- quality improvement
- deep learning
- phase ii
- cervical cancer screening
- body mass index