Serum metabolomics reveals the intervention mechanism and compatible regularity of Chaihu Shu Gan San on chronic unpredictable mild stress-induced depression rat model.

Hongye ZhangHuimin HuangHui SongBonnie ChinHua ZhengJunxiang RuanFang WuBang ChengJinxia WuXuwen LiuYonghong LiangFangming SongZhaoni ChenChaoling TangShiyin LuHongwei GuoZhongmei ZouZhi-Heng Su

Published in: The Journal of pharmacy and pharmacology (2020)

CSGS produced an obvious antidepressant activity. The comprehensive and holistic metabolomics approach could be a powerful tool to study the intervention mechanism and the compatibility rule of traditional Chinese medicine.

Keyphrases

stress induced
randomized controlled trial
mass spectrometry
depressive symptoms
major depressive disorder
sleep quality
physical activity