The neutrophil to lymphocyte ratio (NLR) and the presence of large nodal mass are independent predictors of early response: A subanalysis of the prospective phase II PET-2-adapted HD0607 trial.
Alessandra RomanoChiara PavoniFrancesco Di RaimondoCorrado TarellaSimonetta VivianiAndrea RossiCaterina PattiMarco PicardiMaria CantonettiGiorgio La NasaLivio TrentinSilvia BolisValerio ZoliPaolo GavarottiPaolo CorradiniMichele CimminielloCorrado SchiavottoGuido ParvisRoberta ZanottiGuido GiniAndrés J M FerreriPiera VieroStephane ChauvieAlberto BiggiAlessandro Massimo GianniAndrea GallaminiAlessandro RambaldiPublished in: Cancer medicine (2020)
In advanced-stage HL patients treated with a PET-2-driven strategy, IPS ≥ 3 and NLR > 6 are independent predictors of outcome at diagnosis while the presence of large nodal mass, IPS ≥ 3, and NLR > 6 at diagnosis are independent predictors of early ABVD response.