Capsule-dependent impact of MAPK signalling on host cell invasion and immune response during infection of the choroid plexus epithelium by Neisseria meningitidis.

Rosanna HeroldRené ScholtysikSelina MoroniakChristel WeissHiroshi IshikawaHorst SchrotenChristian Schwerk

Published in: Fluids and barriers of the CNS (2021)

Our data point towards a role of MAPK signalling during infection of the CP epithelium by Nm, which is strongly influenced by capsule expression, and affects infection rates as well as the host cell response.

Keyphrases

immune response
signaling pathway
oxidative stress
poor prognosis
pi k akt
stem cells
photodynamic therapy
single cell
cell therapy
inflammatory response
cell proliferation
mesenchymal stem cells
bone marrow
binding protein
deep learning
data analysis