Feasibility of mesenchymal stem cell culture expansion for a phase I clinical trial in multiple sclerosis.

Sarah Marie PlanchonKaren T LingasJane Reese KoçBrittney M HooperBasabi MaitraRobert M FoxPeter B ImreyKylie M DrakeMicheala A AldredHillard M LazarusJeffrey A Cohen

Published in: Multiple sclerosis journal - experimental, translational and clinical (2018)

Culture expansion of mesenchymal stem cells from multiple sclerosis patients as donors is feasible. However, culture time should be minimized for cell products designated for therapeutic administration.

Keyphrases

multiple sclerosis
mesenchymal stem cells
clinical trial
end stage renal disease
cell therapy
ejection fraction
umbilical cord
newly diagnosed
bone marrow
chronic kidney disease
single cell
peritoneal dialysis
stem cells
randomized controlled trial
study protocol
open label
phase ii