Vitamin D, vitamin D-binding protein, free vitamin D and COVID-19 mortality in hospitalized patients.

Sreedhar SubramanianJonathan M RhodesJoseph M TaylorAnna M MilanSteven LaneMartin HewisonRene F ChunAndrea JorgensenPaul RichardsonDarshan NitchinghamJoseph AslanMaya ShahCoonoor R ChandrasekarAmanda WoodMike BeadsworthMunir Pirmohamed

Published in: The American journal of clinical nutrition (2022)

Vitamin D deficiency, as commonly defined by serum 25(OH)D levels (<50 nmol/L), is not associated with increased mortality from COVID-19, but extremely low (<25 nmol/L) and high (>100 nmol/L) levels may be associated with mortality risks. Neither free nor bioavailable 25(OH)D values are associated with mortality risk. The study protocol was approved by the London-Surrey Research Ethics Committee (20/HRA/2282).

Keyphrases

coronavirus disease
cardiovascular events
sars cov
study protocol
binding protein
randomized controlled trial
public health
clinical trial
type diabetes
open label
respiratory syndrome coronavirus
big data