Diaphragm Muscle Weakness Might Explain Exertional Dyspnea Fifteen Months After Hospitalization for COVID-19.
Binaya RegmiJanina FriedrichBenedikt JörnMehdi SenolAlberto GiannoniMatthias BoentertAyham DaherMichael DreherJens SpiesshoeferPublished in: American journal of respiratory and critical care medicine (2023)
Diaphragm muscle weakness was present 15 months after hospitalization for COVID-19 even in patients who did not require mechanical ventilation, and this weakness was associated with dyspnea on exertion. The current study therefore identifies diaphragm muscle weakness as a correlate for persistent dyspnea in patients after COVID-19 in whom lung and cardiac function are normal. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keyphrases
- mechanical ventilation
- coronavirus disease
- sars cov
- acute respiratory distress syndrome
- intensive care unit
- skeletal muscle
- end stage renal disease
- respiratory failure
- ejection fraction
- chronic kidney disease
- newly diagnosed
- extracorporeal membrane oxygenation
- peritoneal dialysis
- respiratory syndrome coronavirus
- minimally invasive
- prognostic factors
- genome wide
- advanced cancer
- gene expression
- dna methylation
- patient reported