High correlation of temporal muscle thickness with lumbar skeletal muscle cross-sectional area in patients with brain metastases.
Johannes LeitnerSebastian PelsterVeronika SchöpfAnna S BerghoffRamona WoitekUlrika AsenbaumKarl-Heinz NenningGeorg WidhalmBarbara KieselBrigitte GatterbauerKarin DieckmannPeter BirnerDaniela PrayerMatthias PreusserJulia FurtnerPublished in: PloS one (2018)
Our data indicate that TMT, measured on routine cranial MR images, is a useful surrogate parameter for the estimation of skeletal muscle mass in patients with brain metastases. Thus, TMT may be useful for prognostic assessment, treatment considerations, and stratification or a selection factor for clinical trials in patients with brain metastases. Further studies are needed to assess the association between TMT and clinical frailty parameters, and the usefulness of TMT in patients with primary brain tumors.
Keyphrases
- brain metastases
- small cell lung cancer
- skeletal muscle
- clinical trial
- cross sectional
- optical coherence tomography
- insulin resistance
- deep learning
- minimally invasive
- magnetic resonance
- clinical practice
- electronic health record
- convolutional neural network
- type diabetes
- combination therapy
- adipose tissue
- open label
- community dwelling
- smoking cessation