Dopamine D1 + D3 receptor density may correlate with parkinson disease clinical features.
Pengfei YangWilliam C KnightHuifangjie LiYingqiu GuoJoel S PerlmutterTammie L S BenzingerJohn C MorrisJinbin XuPublished in: Annals of clinical and translational neurology (2020)
There is a possibility that we may infer the results in diagnosis, treatment, and prognosis of PD by detecting D1R + D3R as opposed to using dopamine D1 or D3 receptors alone. This is especially true for elderly patients with low D2R expression as is common in this disease.